The End of Symptom-Based Cardiology

Today’s guest is Dr. James Min, the founder and CEO of Cleerly, a cardiovascular imaging company using coronary CT and AI to help clinicians detect and understand heart disease earlier.

In this episode, we explore why traditional cardiology has been so symptom-driven and what changes when physicians can directly visualize the plaque causing coronary artery disease. Jim explains why cholesterol levels, stress tests, and calcium scores can miss important aspects of risk, and how Cleerly is trying to move heart care toward a more personalized, disease-based model. We also discuss the company’s clinical trials, the challenge of building reimbursement and adoption around a new standard of care, and what it took for Jim to move from academic research into entrepreneurship. Finally, we talk about the role AI could play in bringing together imaging, biomarkers, genetics, and other data to make cardiovascular prevention more precise.